Fig. 2: POU2F2 promotes cell proliferation by regulating cell cycle procession. | Cell Death & Disease

Fig. 2: POU2F2 promotes cell proliferation by regulating cell cycle procession.

From: POU2F2 regulates glycolytic reprogramming and glioblastoma progression via PDPK1-dependent activation of PI3K/AKT/mTOR pathway

Fig. 2

A Western blot analyses of POU2F2 expressions in LN229 and U-118 cells transduced with POU2F2 shRNA clones or shRNA scramble. B The effect of POU2F2 on the proliferation of GBM cells was detected by MTT assays. C Image and quantification of GBM cells positive for BrdU staining. D The cell cycle analyses were performed in cells with shCtrl and shPOU2F2. The percentage of cells in the different phases were indicated. E, F Immunoblotting of POU2F2, CCND1, CCNE2, CDK2, CDK4, and CDK6 in GBM cells with or without POU2F2 silence. All data were shown as the mean ± SD, **p < 0.01.

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