Fig. 6: E/M@FA-LPs enhanced oxidative stress. | Cell Death & Disease

Fig. 6: E/M@FA-LPs enhanced oxidative stress.

From: MT1DP loaded by folate-modified liposomes sensitizes erastin-induced ferroptosis via regulating miR-365a-3p/NRF2 axis in non-small cell lung cancer cells

Fig. 6

a Overgeneration of ROS treated with E/M@FA-LPs in A549 and H1299 cells. Scale bar represents 50 μm. b MDA content in different groups of A549 and H1299 cells, E/M@FA-LPs group had the highest MDA overproduction. c Intracellular GSH content in different groups of A549 and H1299 cells; A549 and H1299 cells treated with E/M@FA-LPs show the most obvious GSH decline. d Mitochondrial membrane potential was detected by JC-1. Scale bar represents 25 μm. All experiments were repeated at least three times and representative data are shown. Data are means ± SEM; **p < 0.01.

Back to article page