Fig. 7: Anlotinib restrains the PI3K/AKT signaling pathway via inhibition of VEGFR2 phosphorylation levels in ICC cells. | Cell Death & Disease

Fig. 7: Anlotinib restrains the PI3K/AKT signaling pathway via inhibition of VEGFR2 phosphorylation levels in ICC cells.

From: Anlotinib suppresses tumor progression via blocking the VEGFR2/PI3K/AKT cascade in intrahepatic cholangiocarcinoma

Fig. 7

a Western blot assay was used to detect the expression of cell-cycle-related and apoptosis-related proteins and the phosphate expression of VEGFR2 and AKT in ICC cells in different treatment groups; b schematic depiction of the underlying mechanism of anlotinib-inhibiting tumor activity in ICC cells via the VEGFR2/PI3K/AKT signaling pathway.

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