Fig. 6: The effect of SEPT9 on the number and size of focal adhesions in breast cancer cells and the interaction between SEPT9_i1 and paxillin. | Cell Death & Disease

Fig. 6: The effect of SEPT9 on the number and size of focal adhesions in breast cancer cells and the interaction between SEPT9_i1 and paxillin.

From: SEPT9_i1 regulates human breast cancer cell motility through cytoskeletal and RhoA/FAK signaling pathway regulation

Fig. 6

a IF of FA proteins paxillin in control, SEPT9-KD and SEPT9-Ov cells. IF of SEPT9_i1 (red) and paxillin (green) in SEPT9-Ov cells. b Quantification of FAs and average FA size per nucleus (*p < 0.05, vs control group; p < 0.05, vs Knockdown group). c Interaction between SEPT9_i1 and paxillin by COIP. d Western blot confirming the inhibition in the expression of paxillin in knockdown group and overexpression of SEPT9_i1 promoting the expression of paxillin (*p < 0.05, ***p < 0.001)

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