Fig. 3: The production of anti-DNA Abs is CD4+ T cell-dependent. | Cell Death & Disease

Fig. 3: The production of anti-DNA Abs is CD4+ T cell-dependent.

From: Dendritic cell-associated B7-H3 suppresses the production of autoantibodies and renal inflammation in a mouse model of systemic lupus erythematosus

Fig. 3

Mice at groups of five were depleted with CD4+ T cells by the injection of GK1.5 mAb (700 μg per mouse) i.p. inoculated 2 days before ALD-DNA (a) or BMDC-ALD-DNA (106 cells) (b) immunization. The treatment of mice with GK1.5 were weekly. The serum from each mouse was collected and anti-dsDNA Abs were detected by specific ELISA

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