Fig. 5: Mitotic phosphorylation of SET isoform 1 promotes cell migration and invasion. | Cell Death & Disease

Fig. 5: Mitotic phosphorylation of SET isoform 1 promotes cell migration and invasion.

From: Cyclin-dependent kinase 1-mediated phosphorylation of SET at serine 7 is essential for its oncogenic activity

Fig. 5

ac Cell migration (Transwell) and invasion (Matrigel) assays with cell lines established in Fig. 3a (HeLa). Data were expressed as the mean ± SD of three independent experiments. Migratory and invasive cells were stained with crystal violet and representative fields were shown in c. ***p < 0.001 (unpaired Student’s t test). d, e Cell migration (Transwell) and invasion (Matrigel) assays in RKO cells established in Fig. 4c. Data were expressed as the mean ± SD of three independent experiments. ***p < 0.001 (unpaired Student’s t test). fi Cell migration (Transwell) and invasion (Matrigel) assays in HPNE cells established in Fig. 4f. Data were expressed as the mean ± SD of four independent experiments. ***p < 0.001 (unpaired Student’s t test)

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