Fig. 7: RUNX2 promotes the metastasis of CRC cells in vitro and in vivo. | Cell Death & Disease

Fig. 7: RUNX2 promotes the metastasis of CRC cells in vitro and in vivo.

From: MALAT1 regulates the transcriptional and translational levels of proto-oncogene RUNX2 in colorectal cancer metastasis

Fig. 7

a Migration assays of LoVo or SW620 cells transfected with pcDNA3.1, pcDNA3.1-RUNX2, shRNA-NC, and shRNA–RUNX2, respectively. b Numbers of migrated cells were shown as mean ± SD; n = 3. c Representative results of H&E staining of the metastatic nodules in the lung and liver from six mice subjected to the indicated treatments. d Quantification of lung and liver metastasis from six mice subjected to the indicated treatments. *P < 0.05; **P < 0.01 (t test)

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