Fig. 5: The effect of B7-H3 on the chemoresistance of CRC cells was HK2 dependent in vivo. | Cell Death & Disease

Fig. 5: The effect of B7-H3 on the chemoresistance of CRC cells was HK2 dependent in vivo.

From: B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2

Fig. 5

a Schematic overview of the xenograft tumor model and L-OHP treatment. b The volumes of the B7-H3-overexpressing HCT116 tumors in nude mice following L-OHP treatment. c A representative image of B7-H3-overexpressing HCT116 tumors in nude mice following L-OHP treatment. d The weights of the B7-H3-overexpressing HCT116 tumors in nude mice following L-OHP treatment. e Schematic overview of the xenograft tumor model and 2-DG or L-OHP treatment. f The volumes of the B7-H3-overexpressing HCT116 tumors in nude mice following 2-DG and L-OHP treatment. g A representative image of the overexpressing B7-H3 HCT116 tumors in nude mice following 2-DG and L-OHP treatment. h The weights of the B7-H3-overexpressing HCT116 tumors in nude mice following 2-DG and L-OHP treatment. Values are expressed as means (SEMs). n = 5 mice per group. *P < 0.05

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