Fig. 8: Correlation analysis between the expression of CDX2 and Wnt signaling in human CRC specimens. | Cell Death & Disease

Fig. 8: Correlation analysis between the expression of CDX2 and Wnt signaling in human CRC specimens.

From: CDX2 inhibits the proliferation and tumor formation of colon cancer cells by suppressing Wnt/β-catenin signaling via transactivation of GSK-3β and Axin2 expression

Fig. 8

a Immunohistochemical staining showing the CDX2, β-catenin, c-myc, and cyclin D1 expression in CRC tissues. b, c, d Correlation of the CDX2 staining and the β-catenin (b, r = −0.4794; P < 0.05), cyclin D1 (c, r = −0.5583; P < 0.05) and c-myc (d, r = −4613; P < 0.05) staining. *P < 0.05

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