Fig. 2: u50535 enhances CRC cell proliferation, inhibits apoptosis and accelerates cell cycle. | Cell Death & Disease

Fig. 2: u50535 enhances CRC cell proliferation, inhibits apoptosis and accelerates cell cycle.

From: The novel long noncoding RNA u50535 promotes colorectal cancer growth and metastasis by regulating CCL20

Fig. 2

a CCK8 assays revealed that u50535 silence inhibited HCT116 cell proliferation, while u50535 overexpression promoted DLD1 cell proliferation. b Apoptosis assays by flow cytometry indicated that u50535 silence increased apoptosis rate in HCT116, while u50535 overexpression decreased apoptosis rate in DLD1. c, d Cells in G0/G1 phase were mainly non-proliferation cells. u50535 silence increased the percentage of HCT116 cells in G0/G1 phase, while the overexpression of u50535 inhibited the percentage of DLD1 cells in G0/G1 phase. Data from three independent experiments were expressed as mean ± SD. * P < 0.05; ** P < 0.01