Fig. 1: LIMK2 is progressively downregulated in human CRC tissues. | Cell Death & Disease

Fig. 1: LIMK2 is progressively downregulated in human CRC tissues.

From: Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation

Fig. 1

a IHC analysis of LIMK2 protein expression in 42 paired CRC tissues and adjacent non-tumor tissues (15 from a TMA, 27 from surgery). Representative photographs are shown. b IHC analysis of LIMK2 protein expression in 17 SA tissues and adjacent normal mucosa (the upper panel, magnification, × 400; scale bar: 20 µm; the lower panel, magnification, × 200; scale bar: 50 µm). c IHC scores of normal mucosa, SA and CRC tissues. d Western blot analysis of LIMK2 in 16 paired tumor tissues T and adjacent non-tumor tissues N. Representative photographs are shown. e Real-time PCR analysis of LIMK2 expression of 65 paired human CRC tissues and their adjacent normal mucosa tissues. f LIMK2 expression was detected by western blotting in CRC cell lines

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