Fig. 2 | Cell Death & Differentiation

Fig. 2

From: Diabetes induces the activation of pro-ageing miR-34a in the heart, but has differential effects on cardiomyocytes and cardiac progenitor cells

Fig. 2

Upregulation of miR-34a in diabetic heart. a, b Quantitative scatter plots showing the differential expression of miR-34a by quantitative RT-PCR analysis in the right atrial appendage a and plasma b collected from type-2 diabetic and age-matched non-diabetic individuals undergoing on-pump coronary artery bypass graft surgery. Data are expressed as log-fold change in miR-34a expression and are mean ± SEM. *P < 0.05 and **P < 0.01 vs. non-diabetic. c, d Scatter plots showing the correlation between plasma HbA1c and myocardial miR-34a c or miR-34a and diabetes duration d. There was a positive correlation for both HbA1c level and diabetes duration with myocardial miR-34a expression, and this association was statistically significant. n = 11 in non-diabetic and 10 in diabetic

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