Fig. 1 | Cell Death & Differentiation

Fig. 1

From: Diabetes induces the activation of pro-ageing miR-34a in the heart, but has differential effects on cardiomyocytes and cardiac progenitor cells

Fig. 1

Early upregulation of miR-34a in diabetic individuals. Quantitative scatter plots showing the differential expression of circulating miR-34a by quantitative RT-PCR analysis in the plasma collected from type-2 diabetic individuals with no history of cardiovascular disease at different diabetes duration (n = 11–14 at each time point). Age-matched non-diabetics (ND) served as control (n = 32). Data are expressed as log-fold change in miR-34a expression and are mean ± SEM. **P < 0.01 and ***P < 0.001 vs. ND; ## P < 0.01 vs. diabetic < 5 years duration by one-way ANOVA. b Scatter plots of plasma HbA1c and circulating miR-34a in all the samples used for the study irrespective of the presence or absence of diabetes. There was a strong positive correlation between HbA1c level and miR-34a expression, and this association was statistically significant

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