Fig. 1: Results of CNA burden on ExRs and NRs and overall survival outcome. | British Journal of Cancer

Fig. 1: Results of CNA burden on ExRs and NRs and overall survival outcome.

From: Whole-exome sequencing of long-term, never relapse exceptional responders of trastuzumab-treated HER2+ metastatic breast cancer

Fig. 1

a Total overall genome-wide CNA burden. b Fraction of genome gained. c Fraction of genome lost. d Individual chromosome CNA burden in Chr8 and Chr17 in non-responder (NR) and exceptional responder (ExRs) genomes. e Kaplan–Meier overall survival curves of cases dichotomised by exceptional responder and non-responder. f Total CNA burden, low CNA (total CNA burden < median) and high CNA (total CNA ≥ median). g Overall CNA burden on Chr8, low CNA (Chr8 total CNA burden < median) and high CNA (Chr8 total CNA burden ≥ median). h Overall CNA burden on Chr17, low CNA (Chr17 total CNA burden < median) and high CNA (Chr17 total CNA burden ≥ median).

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