Fig. 1 | British Journal of Cancer

Fig. 1

From: Moving from one to many: insights from the growing list of pleiotropic cancer risk genes

Fig. 1

Examples of pleiotropic genes near a GWAS-identified cancer locus associated with another cancer and/or phenotype in a relevant condition. Each gene represents a pleiotropic locus that is associated with multiple cancer types and/or one cancer type, and cancer-related traits and biomarkers. Connections in this chord diagram indicate that variants in or near respective genes associate with both a cancer type and one or more phenotypes within the linked conditions. The width of the chord corresponds to the number of phenotypes within the respective area; for example, the widest chord between TERT and Other cancer represents association between the TERT locus and 12 different cancers

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