Table 4 Risk of obesity-related cancer in men and women according to change in weight status during middle age

From: Midlife weight gain is a risk factor for obesity-related cancer

Weight status change N Baseline BMIa Follow-up BMIa HR (95% CI)b
Men
  Did not become overweightc 1389 25.6 26.2 1.00
  Became overweightd 206 27.8 32.0 2.18 (1.33, 3.56)
  Sustained overweighte 248 32.9 34.4 1.28 (0.76, 2.14)
Women
  Did not become overweightc 970 21.5 22.4 1.00
  Became overweightd 468 22.9 27.8 1.60 (1.12, 2.28)
  Sustained overweighte 569 29.6 32.2 1.33 (0.94, 1.88)
  1. BMI body mass index, CI confidence interval, HR hazards ratio.
  2. aMean BMI at baseline and at the end of weight change period (average follow-up of 14 years).
  3. bAdjusted for age, average adult height, education, cigarettes per day, alcohol intake and physical activity.
  4. cWomen with BMI <25 kg/m2 and men with BMI <30 kg/m2 at baseline who had no change in BMI category over ~14-year weight change period.
  5. dWomen with BMI <25 kg/m2 at baseline who had BMI ≥25 kg/m2 at the end of weight change period; men with BMI <30 kg/m2 at baseline who developed BMI ≥30 kg/m2 at the end of weight change period.
  6. eWomen with BMI ≥25 kg/m2 and men with BMI ≥30 kg/m2 at baseline who remained overweight throughout weight change period