Table 2 Risk of obesity-related cancers according to category of weight change

From: Midlife weight gain is a risk factor for obesity-related cancer

Weight changea N PY Cases I/1000 py HR (95% CI)b
All subjects
  Weight loss 235 3631 20 5.51 1.05 (0.65, 1.69)
  Weight stable 2280 35,901 173 4.82 1.00
  Weight gain 1335 19,180 117 6.1 1.38 (1.09, 1.76)
Men
  Weight loss 145 2210 12 5.43 1.17 (0.62, 2.18)
  Weight stable 1168 18,274 74 4.05 1.00
  Weight gain 530 7568 34 4.49 1.32 (0.88, 2.00)
Women
  Weight loss 90 1421 8 5.63 0.87 (0.41, 1.84)
  Weight stable 1112 17,627 99 5.62 1.00
  Weight gain 805 11,613 83 7.15 1.39 (1.03, 1.87)
  1. CI confidence interval, I/1000 py incidence of cancer cases per 1000 person-years, HR hazards ratio.
  2. aWeight loss = loss of 0.45 kg or more per year, weight gain = gain of 0.45 kg or more per year, weight stable = loss or gain of <0.45 kg/year.
  3. bAdjusted for sex (for all subjects model), age, average adult height, education, cigarettes per day, alcohol intake, physical activity, and BMI at baseline