Heo H, Bae J-H, Amano A, Park T, Choi Y-H. Supplemental or dietary intake of omega-3 fatty acids for the treatment of periodontitis: a meta-analysis. J Clin Periodontol 2022; 49: 362-377.
Supplemental or dietary intake of omega-3 fatty acids for the treatment of periodontitis may have a positive impact on the disease.
This meta-analysis aimed to evaluate the intervention effect of omega-3 fatty acids on changes in periodontal parameters. Studies published in English between 2010 and 2020 were extracted from the Cochrane Library, EMBASE and PubMed databases. The effects of omega-3 fatty acid intervention were investigated using the amount of omega-3 intake, periodontal pocket depth (PPD), clinical attachment loss (CAL) and bleeding on probing (BOP). All 13 studies included in the meta-analysis were interventional, randomised controlled trials. Two studies implemented omega-3 fatty acid-rich diets, while eleven studies used supplements. Risk of bias was low and publication bias was not shown. Meta-analysis showed a statistically significant PPD reduction, CAL gain and BOP reduction for the omega-3 fatty acid intervention overall.
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Wadia, R. Periodontitis and omega-3 fatty acids. Br Dent J 232, 533 (2022). https://doi.org/10.1038/s41415-022-4212-z