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Decitabine may improve CAR-T efficacy in refractory/relapsed acute leukemia patients carrying TP53 alterations

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Acknowledgements

We would like to thank Dr. Robert Gale for reviewing our paper. We also thank all members of the study team, the patient, and their family. This work was supported by research grants from National Natural Science Foundation of China (81873443 and 81400155), National Science and Technology Major Project (2017ZX09304021), National Key R&D Program of China (2016YFC0902800), Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), Frontier Clinical Technical Project of the Science and Technology Department of Jiangsu Province (BE2017655), Jiangsu Provincial Medical Talent (ZDRCA2016045), Jiangsu Natural Science Foundation of China (BK20140374), Top-notch Young Health Talents, 5th Suzhou Health Professionals Program (GSWS2019035), Major Natural Science Research Projects in institutions of higher education of Jiangsu Province (19KJA210002), and the Key Science Research Project of Jiangsu Commission of Health (K2019022).

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Qu, C., Song, Y., Yin, J. et al. Decitabine may improve CAR-T efficacy in refractory/relapsed acute leukemia patients carrying TP53 alterations. Bone Marrow Transplant 56, 1710–1713 (2021). https://doi.org/10.1038/s41409-021-01230-z

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