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Building a hematopoietic cell transplantation outcomes registry in Mexico


The aim of this study was to assess the feasibility of hematopoietic cell transplantation (HCT) data collection using an electronic platform at Mexican centers. Four public centers performing HCT in adults were included. A cloud-based electronic platform in Spanish was developed to allow real-time registration of demographic, clinical, and outcomes variables. Data were obtained from paper and electronic medical records and institutional databases. Data managers were hired to perform the collection. Data from January 2015 to December 2018 were retro and prospectively collected during a 10-month period. From 2015 to 2018, 473 HCT were performed. Most were autologous (55%). Patients undergoing autologous HCT had the highest median age (49 years) compared with patients undergoing allogeneic (34 years) or haploidentical HCT (29 years). The most common underlying disease for autologous HCT was multiple myeloma. Acute leukemias were the most common diagnoses among allogeneic and haploidentical HCT recipients. Two-year nonrelapse mortality was 2.5%, 18%, and 18% for autologous, allogeneic, and haploidentical HCT, respectively. We determined it was feasible to start a multicenter collaborative study in Mexico as it was very well received by the physicians and it can lead to the creation of a Mexican HCT Registry in the near future.

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Fig. 1: Algorithm of data collection.
Fig. 2: Number of HCT by type and year.
Fig. 3


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We would like to thank the data managers Edgar, Margarita, and Melissa who participated in this project.


This work was funded by a 2018 Conquer Cancer Foundation of ASCO Global Oncology Young Investigator Award (ID 12996). Any opinions, findings, and conclusions expressed in this material are those of the authors and do not necessarily reflect those of the American Society of Clinical Oncology® or the Conquer Cancer Foundation.

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Correspondence to Eucario Leon-Rodriguez.

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Rivera-Franco, M.M., Leon-Rodriguez, E., Gómez-Almaguer, D. et al. Building a hematopoietic cell transplantation outcomes registry in Mexico. Bone Marrow Transplant 55, 2279–2285 (2020).

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