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Nutritional risk index as a risk factor for breakthrough candidemia in allogeneic hematopoietic stem cell transplantation

Bone Marrow Transplantation volume 55, pages 661–664 (2020)Cite this article

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To the Editor,

Certain allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients develop candidemia even while undergoing antifungal therapy; this is known as breakthrough candidemia (BC) [1]. Despite advances in antifungal agents, BC remains a fatal complication in allo-HSCT recipients with a mortality rate of 40–50% [2]. The purpose of this study was to describe the clinical characteristics and identify the risk factors of BC in allo-HSCT using a matched-pair analysis due to the limited data available. This study was performed in accordance with the Declaration of Helsinki and approved by the ethics committee of our hospital. Statistical analyses were performed with EZR [3].

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Acknowledgements

The authors would like to thank the nursing staff at Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, for their excellent patient care.

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Authors and Affiliations

  1. Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan

    Satoshi Kaito, Yuho Najima, Atsushi Wada, Hiroto Adachi, Ryosuke Konuma, Yuya Kishida, Akihito Nagata, Tatsuya Konishi, Yuta Yamada, Takuma Kumagai, Kyoko Inamoto, Kota Yoshifuji, Megumi Akiyama, Takashi Toya, Aiko Igarashi, Hideharu Muto, Noriko Doki, Takeshi Kobayashi, Kazuhiko Kakihana & Kazuteru Ohashi

  2. Department of Infection Prevention and Control, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan

    Satoshi Kaito & Noritaka Sekiya

  3. Department of Clinical Laboratory, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan

    Noritaka Sekiya & Tomokazu Suzuki

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  1. Satoshi Kaito
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  2. Noritaka Sekiya
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Correspondence to Noritaka Sekiya.

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Kaito, S., Sekiya, N., Najima, Y. et al. Nutritional risk index as a risk factor for breakthrough candidemia in allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant 55, 661–664 (2020). https://doi.org/10.1038/s41409-019-0541-1

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