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Transmission of chromosomally integrated human herpes virus-6A via haploidentical stem cell transplantation poses a risk for virus reactivation and associated complications

Bone Marrow Transplantation (2019) | Download Citation

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L.O. and A.K. are participants in the BIH‐Charité Clinician Scientist Program funded by the Charité – Universitätsmedizin Berlin and the Berliner Institut für Gesundheitsforschung (BIH). This work was supported by a grant to L.O. from Bild Hilft e.V. – Ein Herz für Kinder and by the HHV-6 Foundation, who provided the anti-gp82/105 antibody. The anti-IE-1 antibody was kindly provided by L. Flamand and colleagues from the Laval University (Sainte-Foy, Quebec, Canada). We thank Kathy Astrahantseff for proofreading of the manuscript.

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Author notes

  1. These authors contributed equally: Lena Oevermann, Cosima Zimmermann


  1. Department of Pediatric Hematology and Oncology, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany

    • Lena Oevermann
    • , Sebastian Voigt
    • , Annette Künkele
    • , Angelika Eggert
    • , Johannes H. Schulte
    •  & Hedwig E. Deubzer
  2. Berliner Institut für Gesundheitsforschung (BIH), Anna-Louisa-Karsch-Strasse 2, 10178, Berlin, Germany

    • Lena Oevermann
    • , Annette Künkele
    • , Angelika Eggert
    • , Johannes H. Schulte
    •  & Hedwig E. Deubzer
  3. German Cancer Consortium (DKTK), Partner Site Berlin, Berlin, Germany

    • Lena Oevermann
    • , Angelika Eggert
    • , Johannes H. Schulte
    •  & Hedwig E. Deubzer
  4. German Cancer Research Center (DKFZ), Heidelberg, Germany

    • Lena Oevermann
    • , Angelika Eggert
    • , Johannes H. Schulte
    •  & Hedwig E. Deubzer
  5. Institute of Virology, Freie Universität Berlin, Robert-von-Ostertag-Strasse 7-13, 14163, Berlin, Germany

    • Cosima Zimmermann
    •  & Benedikt B. Kaufer
  6. Department of Infectious Diseases, Robert Koch Institute, Seestrasse 10, 13353, Berlin, Germany

    • Sebastian Voigt
  7. Department of Pediatric Hematology and Oncology, Kinderkrankenhaus, Amsterdamer Strasse 59, 50735, Köln, Germany

    • Stephan Lobitz
  8. Neuroblastoma Research Group, Experimental and Clinical Research Center (ECRC) of the Charité and the Max-Delbrück-Center for Molecular Medicine (MDC) in the Helmholtz Association, Lindenberger Weg, 8013125, Berlin, Germany

    • Hedwig E. Deubzer


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The authors declare that they have no conflict of interest.

Corresponding author

Correspondence to Lena Oevermann.

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