Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Hematopoietic stem cell transplantation for cytidine triphosphate synthase 1 (CTPS1) deficiency

This is a preview of subscription content

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

References

  1. Martin E, Palmic N, Sanquer S, Lenoir C, Hauck F, Mongellaz C, et al. CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation. Nature. 2014;510:288–92.

    CAS  Article  Google Scholar 

  2. Wynn RF, Arkwright PD, Haque T, Gharib M, Wilkie G, Morton-Jones M, et al. Treatment of Epstein-Barr-virus-associated primary CNS B-cell lymphoma with allogeneic T-cell immunotherapy and stem-cell transplantation. Lancet Oncol. 2005;6:344–46.

    Article  Google Scholar 

  3. Güngör T, Teira P, Slatter M, Stussi G, Stepensky P, Moshous D, et al. Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study. Lancet. 2014;383:436–48.

    Article  Google Scholar 

  4. Naik S, Nicholas S, Martinez C, Leen A, Hanley P, Gottschalk S, et al. Adoptive immunotherapy for primary immunodeficiency disorders with virus-specific cytotoxic T-lymphocytes. J Allergy Clin Immunol. 2016;137:1498–505.

    CAS  Article  Google Scholar 

  5. Trück J, Kelly DF, Taylor JM, Kienzler A, Lester T, Seller A, et al. Variable phenotype and discrete alterations of immune phenotypes in CTP synthase 1 deficiency: report of 2 siblings. J Allergy Clin Immunol. 2016;ume 138:1722–5.

    Article  Google Scholar 

  6. Kucuk ZY, Zhang K, Filipovich L, Blessing J. CTP synthase 1 deficiency in successfully transplanted siblings with combined immune deficiency and chronic active EBV infection. J Clin Immunol. 2016;36:750–3.

    Article  Google Scholar 

  7. Dvorak CC, Cowan MJ. Hematopoietic stem cell transplantation for primary immunodeficiency disease. Bone Marrow Transplant. 2008;41:119–26.

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Zohreh Nademi.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Nademi, Z., Wynn, R.F., Slatter, M. et al. Hematopoietic stem cell transplantation for cytidine triphosphate synthase 1 (CTPS1) deficiency. Bone Marrow Transplant 54, 130–133 (2019). https://doi.org/10.1038/s41409-018-0246-x

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41409-018-0246-x

Further reading

Search

Quick links