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Efficacy and safety of keratinocyte growth factor (palifermin) for prevention of oral mucositis in TBI-based allogeneic hematopoietic stem cell transplantation

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The study was conducted in cooperation with the Eastern German Study Group of Haematology and Oncology (OSHO, protocol code OSHO #76). Palifermin (Kepivance®) was provided by Swedish Orphan Biovitrum AB (Sobi), SE-112 76 Stockholm, Sweden. We further thank GMIHO (Gesellschaft für medizinische Innovation/Hämatologie und Onkologie mbH, Berlin, Germany) for the technical support of this trial, and Dr. Andreas Engelen (WiSP—Wissenschaftlicher Service Pharma GmbH, Langenfeld, Germany) for data monitoring and biostatistics.

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Correspondence to Herbert G. Sayer.

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The authors declare that they have no conflict of interest.

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Support: Palifermin was provided by Swedish Orphan Biovitrum

EudraCT database: 2006-003683-54.

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Schmidt, V., Niederwieser, D., Schenk, T. et al. Efficacy and safety of keratinocyte growth factor (palifermin) for prevention of oral mucositis in TBI-based allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant 53, 1188–1192 (2018).

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