Fig. 3: Exploratory whole-brain analysis of changes in task-based activation and resting-state functional connectivity (rsFC) following 4 weeks of the intervention. | Translational Psychiatry

Fig. 3: Exploratory whole-brain analysis of changes in task-based activation and resting-state functional connectivity (rsFC) following 4 weeks of the intervention.

From: A digital intervention targeting cognitive control network dysfunction in middle age and older adults with major depression

Fig. 3

a Greater activation at post-EVO in the right middle frontal gyrus (MFG) during the Stroop/Flanker task for incongruent trials relative to congruent trials; voxel threshold: p < 0.005, cluster threshold: p < 0.07. b Increased functional connectivity from pre- to post-EVO from the left MFG seed to the right MFG and the right MFG seed to the right superior temporal gyrus (STG) and right inferior frontal gyrus (IFG); voxel threshold: p < 0.001, cluster threshold: p < 0.05.

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