Table 1 Summary of demographic and postmortem characteristics of human subjects.

From: Involvement of the nuclear factor-κB transcriptional complex in prefrontal cortex immune activation in bipolar disorder

Parameter Unaffected comparison Bipolar disorder (%)
N 35 35
Sex 20M/15F 20M/15F
Race 32W/3B 34W/1B
Age (years) 46.4 ± 12.7 45.5 ± 12.2
Postmortem interval (h) 19.1 ± 5.1 20.5 ± 7.0
Freezer storage time (months) 103.0 ± 49.8 109.9 ± 45.1
Brain pH 6.7 ± 0.3 6.6 ± 0.3
RNA integrity number 8.1 ± 0.6 8.0 ± 0.6
Medications at time of deatha
Antipsychotic 12 (34.3)
Antidepressant 22 (62.9)
Benzodiazepine/anticonvulsant 16 (45.7)
Lithium 3 (8.6)
  1. The mean (±standard deviation) age, postmortem interval, RNA integrity number (RIN), brain pH, and tissue freezer storage time did not differ between bipolar disorder subjects and their matched unaffected comparison subjects (all t(68) ≤ 0.96, p ≥ 0.34).
  2. aFor medications at time of death, the number and percentage (in parentheses) of subjects in each applicable category are provided.