Fig. 2: Transcript levels of NF-κB-related mRNAs in the PFC in bipolar disorder. | Translational Psychiatry

Fig. 2: Transcript levels of NF-κB-related mRNAs in the PFC in bipolar disorder.

From: Involvement of the nuclear factor-κB transcriptional complex in prefrontal cortex immune activation in bipolar disorder

Fig. 2

Open circles represent mRNA levels for each bipolar disorder subject relative to the matched unaffected comparison subject. Data points to the left of the unity line indicate higher mRNA levels in the bipolar disorder subject relative to the comparison subject. Percent difference in diagnostic group means and primary statistical analysis results with Bonferroni-Holm adjusted p values are provided for each transcript. Mean ± standard deviation mRNA levels for unaffected comparison subjects and bipolar disorder subjects, respectively, are: IL-1R (0.0017 ± 0.00057 and 0.00259 ± 0.0018); TNFR (0.00962 ± 0.0018 and 0.0127 ± 0.0058); NF-κB1 (0.0051 ± 0.00058 and 0.0054 ± 0.00085); NF-κB2 (0.00196 ± 0.00041 and 0.00296 ± 0.0017); RelA (0.0123 ± 0.0013 and 0.0141 ± 0.0030); RelB (0.00228 ± 0.00034 and 0.00245 ± 0.00087); cRel (0.00468 ± 0.00054 and 0.00526 ± 0.0011); IFITM1 (0.0146 ± 0.0029 and 0.0190 ± 0.0064); IFITM2/3 (0.014 ± 0.0044 and 0.0199 ± 0.011); and HIVEP2 (0.0817 ± 0.010 and 0.075 ± 0.010).

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