Table 1 The CPT scores at week 12 from baseline between the EPA and placebo groups

From: High-dose eicosapentaenoic acid (EPA) improves attention and vigilance in children and adolescents with attention deficit hyperactivity disorder (ADHD) and low endogenous EPA levels

Mean (SD)EPA (n = 48)Placebo (n = 44)P
BaselineWk12ChangesBaselineWk12Changes
d’−1.27 (0.92)−1.41 (1.15)−0.14 (0.63)−1.23 (0.85)−1.60 (0.98)−0.36 (0.63)0.094
OM0.09 (0.08)0.08 (0.10)−0.01 (0.09)0.07 (0.07)0.07 (0.07)0.00 (0.06)0.615
COM0.53 (0.16)0.49 (0.20)−0.04 (0.15)0.58 (0.16)0.48 (0.18)−0.10 (0.13)0.025*
PER0.04 (0.05)0.04 (0.03)−0.01 (0.03)0.04 (0.05)0.03 (0.03)−0.01 (0.04)0.604
HRT509.40 (117.91)210.74 (117.99)1.34 (61.87)481.72 (107.89)508.06 (119.67)26.34 (63.44)0.059
HRTSD299.20 (166.61)293.10 (164.84)−6.10 (108.48)266.26 (156.23)274.11 (148.29)7.85 (128.01)0.573
VAR139.21 (98.08)133.81 (88.80)−15.44 (83.50)117.36 (81.98)132.91 (86.45)14.15 (72.19)0.041#*
HRTBC11.08 (25.58)15.57 (29.62)4.49 (45.50)12.01 (17.98)14.21 (17.95)2.21 (22.22)0.650#
HRTISIC73.93 (45.66)73.32 (44.38)−0.61 (44.05)63.61 (51.51)69.05 (51.47)5.44 (39.84)0.492
  1. Changes indicates the changes in scores from baseline at week 12, COM commission error, CPT continuous performance test, d’ detection, EPA eicosapentaenoic acids, HRT hit reaction time, HRTSD HRT standard deviation, VAR variability, HRTBC HRT block change, HRTISIC HRT interstimulus interval change, n number; PER perseveration, SD standard deviation, wk week. The p values are from Independent-sample t-test, unless Mann–Whitney test result
  2. #Mann–Whitney test results
  3. Asterisk (*) indicates a statistical significance of p < 0.05