Fig. 1: Decreased sperm miRNA expression in men with extensive adverse childhood experiences. | Translational Psychiatry

Fig. 1: Decreased sperm miRNA expression in men with extensive adverse childhood experiences.

From: Reduced levels of miRNAs 449 and 34 in sperm of mice and men exposed to early life stress

Fig. 1

a qPCR analysis of miR-449a, miR-449b-5p, miR-34b-3p, miR-34c-5p, miR-152-3p, and miR-375-3p in sperm RNA from low ACE group (score 0–1, n = 5) vs. high ACE group (score >4, n = 5). Wilcoxon rank-sum test *P < 0.05, **P < 0.01. Data represented as mean ± SEM. bc Correlation plot comparing relative expression of miR-449a to miR-449b (b) and miR-34b to miR-34c (c) for individual samples fitted with single-variable linear regression. n = 10, r = Spearman’s coefficient with exact p value listed. Each point represents an individual sample

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