# Table 1 Median and interquartile range of the average phases, MESORs and amplitudes of the daily sinusoid fits for each of the participant groups, the difference between phases of each modality, and statistical significance pairwise comparisons across the three groups (BD n = 36, BPD n = 22 and HC n = 25) using the Wilcoxon statistical hypothesis test

Within group phase differences tested against zero mean
BD BPD HC BD (FDR) BPD (FDR) HC (FDR)
HR-ACT (mean ± std) 0.72 ± 4.17 3.11 ± 3.08 0.46 ± 4.06 0.017 <0.001 0.246
HR-SLP (mean ± std) 0.56 ± 3.41 0.99 ± 1.66 −0.83 ± 2.11 0.006 0.006 0.051
ACT-SLP (mean ± std) −0.16 ± 2.90 −2.12 ± 3.21 −1.29 ± 2.87 0.180 0.005 0.004
Group differences in phase, MESOR and amplitude
BD BPD HC BD vs BPD (FDR) BD vs HC (FDR) BPD vs HC (FDR)
Activity
Phase (mean ± std) 14.09 ± 2.83 12.34 ± 3.57 12.82 ± 3.31 0.253 0.410 0.403
MESOR (mean ± std) 0.014 ± 0.004 0.013 ± 0.003 0.014 ± 0.004 0.276 0.418 0.418
Amplitude (mean ± std) 0.0033 ± 0.0021 0.0026 ± 0.0014 0.0027 ± 0.0013 0.294 0.401 0.380
Sleep
Phase (mean ± std) 14.25 ± 1.68 14.46 ± 2.07 14.12 ± 1.31 0.398 0.483 0.391
MESOR (mean ± std) 0.35 ± 0.08 0.34 ± 0.07 0.36 ± 0.07 0.477 0.411 0.385
Amplitude (mean ± std) 0.11 ± 0.02 0.11 ± 0.03 0.11 ± 0.02 0.325 0.444 0.276
Heart rate
Phase (mean ± std) 14.81 ± 3.21 15.45 ± 2.07 13.28 ± 2.37 0.384 0.086 0.051
MESOR (mean ± std) 75.24 ± 7.08 77.65 ± 5.69 74.48 ± 2.62 0.251 0.425 0.275
Amplitude (mean ± std) 8.10 ± 2.54 8.67 ± 3.45 7.41 ± 2.62 0.369 0.300 0.289
1. To test phase differences against zero mean within groups, a Mann–Whitney test was used at 5% significance level. Correction for multiple testing was performed using the false discovery rate (FDR)
2. Statistically significant differences at the p = 0.05 level appear in bold. avPhase, avMESOR and avAmplitude denote the mean of the phases, MESORs and amplitudes of the daily sinusoid fits. The units of all phase measures are shown in hours