Fig. 5 | The ISME Journal

Fig. 5

From: Multiple mechanisms drive phage infection efficiency in nearly identical hosts

Fig. 5

Expression of host18’s restriction/modification (R/M) and translation genes in response to phi18:3 and phi38:1. OE over expressed; UE under expressed. Represented in a stacked bar graph is the fold change of expression of infected relative to uninfected cells, normalized by the fraction of infected cells. Solid bars represent the differential expression values whereas dotted bars represent the non-differentially expressed genes. a The R/M system is clearly differentially expressed in response to phi18:3; mostly OE throughout the infection; and UE occurs during middle infection with phi38:1. Host18 displays basal expression (non-differentially expressed genes) of the R/M system regardless of phage infection. b Host18 genes involved in protein translation are OE 4.5-fold (early), 1.7-fold (middle), and 1.4-fold (late) higher in response to phi18:3 than to phi38:1. The values of expression in host18 infected with phi38:1 do not significantly increase over time (t-test, p-value > 0.05; Supplementary Dataset S1 Tab. 7). Host18 displays basal expression (non-differentially expressed genes) of the translation genes regardless of phage infection. Time 0 represents the dilution of the infection after a 15-min adsorption

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