There are considerable risks for vertebral artery (VA) injury in case of corrective surgery for a severe and rigid cervical kyphotic deformity. This case report describes a rare case of surgical management for pre-existing traumatic rigid cervical kyphosis associated with unilateral VA occlusion.
A 73-year-old male fell down and injured his neck. He was referred to our hospital 10 months after injury because his degree of head drop progressed gradually to a chin-on-chest position such that he could not look straight forward. On plain X-ray, the C2–7 angles in the neutral, flexion, and extension positions were 61°, 71°, and 50°, respectively. CT revealed a collapse of the C5 vertebral body and bone fusion between C4 and C5 in the anterior vertebrae, and unilateral VA occlusion was confirmed by angiography. Two-stage surgery was planned to correct the kyphosis. In the first stage, anterior release of the C4/5 bone-spur fusion and dissection of the intervertebral disk were performed. After release, angiography confirmed neither occlusion nor rupture of the VA. In the second stage, anterior and posterior fixation was performed at correcting position while maintaining slight kyphosis in order to avoid excessive distortion of the VA. The postoperative C2–7 kyphosis angle improved to 16° without any VA injury, and the patient could look forward easily.
The degree of correction as well as risk management of VAs should be considered carefully during corrective surgery for severe and rigid cervical kyphosis, especially with unilateral VA occlusion.
There are considerable risks for vertebral artery (VA) injury in corrective surgery of a cervical deformity; therefore, adequate risk management is necessary to avoid VA injury. Here, we describe a rare case of surgical management for pre-existing traumatic rigid cervical kyphosis associated with unilateral VA occlusion. We highlight the importance of evaluating VAs and the appropriate degree of correction for cervical kyphosis.
The patient was a 73-year-old male with mental retardation who was living at a special care facility. He could perform the activities of daily living independently and had neither a specific motor disability nor appreciable disease. He fell down and injured his neck 1 year earlier, but the underlying mechanism of the injury was unclear. He had been treated conservatively at an orthopedic clinic, and no neurological deficit was seen. However, he was referred to our hospital at 10 months after injury because his degree of head drop progressed gradually to the extent that he could not look straight forward. He could not walk safely because his visual field was lower.
At the initial examination, his head had dropped to a chin-on-chest position. Moreover, his neck was so rigid that it could not be extended passively. There was no observable neurological deficit. On plain X-ray, a kyphotic deformity was seen by functional imaging of the cervical spine; C2–7 angles in the extension (a), neutral (b), and flexion (c) positions were 50°, 61°, and 71°, respectively (Fig. 1). Computed tomography (CT) revealed a collapse of the C5 vertebral body, bone spur fusion in the anterior vertebrae, and disassociation of the interspinous process interval between C4 and C5. On T2-weighted sagittal images from magnetic resonance imaging (MRI), no obvious cord compression was observed (Fig. 2). An occlusion of the right VA was confirmed in CT and MR angiography (Fig. 3). Taken together, the patient was diagnosed as delayed kyphotic deformity associated with VA occlusion following cervical spine trauma. With an aim to improve his frontal gaze disturbance and kyphotic deformity, surgical correction and fixation of the cervical spine was performed.
Two-stage surgery was planned. In the first stage, anterior release of the C4–5 bone-spur fusion and dissection of the intervertebral disk were performed (surgery time: 200 min; estimated blood loss: 15 mL). After release, the cervical spine was distracted and extended gradually as much as possible and a hard collar was applied for external fixation. Then, the VA was evaluated by CT angiography. At this time, C2–7 kyphosis angle was 35° without any progression of VA occlusion associated with cervical spine extension.
In the second stage, at 2 days after the initial surgery, posterior release and instrumental fixation with pars and pedicle screws on C2–7 and anterior corpectomy of the C5 vertebral body with implantation of an autologous ilium bone were performed (surgery time: 360 min; estimated blood loss: 339 mL). After surgery, C2–7 kyphosis angle improved to 16° (Fig. 4). On postoperative CT and MR angiography, no progression of VA occlusion was confirmed (Fig. 5). The patient’s visual field became upper and wider and he could look forward easily. He was discharged and neurological impairment has not been observed consistently until 12 months post surgery.
Cervical malalignment contributes to the pathogenesis of cervical myelopathy. It has been shown, in cadaver and animal models, that an increase in sagittal kyphosis leads to greater cord tension, flattening, and an increase in intramedullary pressure, resulting in neurological compromise [1,2,3,4,5,6]. VA injury accounts for 17–46% of cervical spine traumas, of which 0–45% are symptomatic and 0–18% are considered life-threatening complications [7,8,9,10,11,12,13,14]. It is also reported that 50–70% of traumatic VA injury is accompanied with a cervical spine fracture and spinal cord injury . When performing posterior cervical spinal instrumentation surgery, precise evaluation of VA and circle of Willis is usually required to avoid VA injury and concurrent associated complications [15,16,17].
As far as we are aware, the incidence of VA injury during corrective surgery of the cervical spine is unclear. However, complications of related medical procedures for cervical kyphosis have been reported [17,18,19,20,21,22]. Horsley reported longitudinal traction-induced rupture of VA aneurysm in a case with neurofibromatosis type I and severe cervical kyphosis . Willis reported that there are potential risks for embolus formation associated with vasospasm or intimal injury when VA is distorted and/or stretched due to fracture dislocation . Thus, before surgical reduction or/and correction, VAs should be evaluated by angiography to reduce the risk of VA injury .
In this case, we performed corrective fusion surgery for delayed rigid kyphotic deformity of the cervical spine associated with unilateral VA occlusion. To prevent damage to the existing dominant VA, we evaluated the VAs in neck-extended position by angiography, when cervical spine mobility was obtained by anterior release. After confirming the safety of the dominant VA, we then performed anterior and posterior fixation at the correcting position. Excessive correction might lead to vasospasm, rupture, or occlusion of the dominant VA, which could result in brain stem damage that might be fatal. Therefore, we were prepared to discontinue the correction if any sign of VA injury was observed. Fortunately, no sign of progression was confirmed during the first stage of surgery, and we proceeded to the second stage of surgery 2 days later. Although we avoided excessive correction and left some kyphosis (post-operative C2–7 kyphotic angle improved to 16°), frontal gaze disturbance was resolved and the patient has been able to lead a normal daily life.
In conclusion, it is important that not only adequate risk management for VAs but also appropriate correction should be considered carefully for corrective surgery of cervical kyphosis, especially in patients with unilateral VA occlusion.
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Conflict of interest
The authors declare that they have no conflict of interest.
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Konomi, T., Suda, K., Matsumoto, S. et al. Two-stage corrective surgery for severe rigid cervical kyphotic deformity with unilateral vertebral artery occlusion after old blunt trauma: a case report. Spinal Cord Ser Cases 4, 18 (2018). https://doi.org/10.1038/s41394-018-0051-1