Fig. 1 | Signal Transduction and Targeted Therapy

Fig. 1

From: Dickkopf-1 contributes to hepatocellular carcinoma tumorigenesis by activating the Wnt/β-catenin signaling pathway

Fig. 1

DKK1 expression is increased in HCC tissues. The expression of DKK1 in human liver tissues was evaluated by immunohistochemistry and qRT-PCR. The results revealed weak expression (DKK1− or +) in 22 of 22 human cirrhotic tissue samples (a, b). Upregulated DKK1 expression (DKK1++ or +++) was observed in 48 of 53 human HCC tumor samples (c, d). Scale bar = 100 μm. Thirty-three pairs of fresh HCC and corresponding peritumoral liver tissues were used for qRT-PCR analysis (e)

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