Table 4 Number of CPIP components at 12 months CGA

From: The role of recombinant human CC10 in the prevention of chronic pulmonary insufficiency of prematurity

CohortNumber of componentsN (%) infants surviving without CPIP at 12 months CGAaN (%) infants without CPIP in survivors at 12 months CGAb
  PlaceborhCC10P valuePlaceborhCC10P value
Cohort 1N2222 2220 
 None1 (5)1 (5)>0.91 (5)1 (5)>0.9
 ≤1 component5 (23)3 (14)0.45 (23)3 (15)0.5
 ≤2 components13 (59)7 (32)0.0713 (59)7 (35)0.1
 ≤3 components21 (95)13 (59)0.00421 (95)13 (65)0.01
Cohort 2N2123 1918 
 None3 (14)3 (13)0.93 (16)3 (17)0.9
 ≤1 component5 (24)6 (26)0.95 (24)6 (33)0.6
 ≤2 components8 (38)7 (30)0.68 (42)7 (39)0.8
 ≤3 components13 (62)10 (43)0.213 (68)10 (56)0.4
  1. CGA corrected gestational age, CPIP chronic pulmonary insufficiency of the prematurity, rhCC10 recombinant human Club cell 10-kilodalton protein
  2. aImputed worst-case scenario for missing data
  3. bNo imputation for missing data; denominators reflect the numbers of patients for whom data were collected at this time point