Table 1 TMCC3 silencing of AS-B145 and AS-B634 reduces their tumor-initiating capacitiesa.

From: Transmembrane and coiled-coil domain family 3 (TMCC3) regulates breast cancer stem cell and AKT activation

   (Cell number of injection) Stem cell frequency p value
   105 5 × 104 104 103 102 50
AS-B145 shControl 5/5 5/6 3/5     1:19,707 0.014
shTMCC3 4/5 3/7 1/5     1:70,682  
AS-B634 shControl    8/8 5/5 4/5 3/5 1:59 <0.001
shTMCC3    8/8 3/5 1/5 0/5 1:987  
  1. aBCSC-enriched population of AS-B145 and AS-B634 were infected with shTMCC3 #B or shControl and injected into mammary fat pads of NSG mice.