Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Using metabolic imaging to investigate neuromodulatory mechanisms of rTMS

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Get just this article for as long as you need it


Prices may be subject to local taxes which are calculated during checkout


  1. Cuypers K, Marsman A. Transcranial magnetic stimulation and magnetic resonance spectroscopy: Opportunities for a bimodal approach in human neuroscience. NeuroImage. 2021;224:117394.

    Article  CAS  PubMed  Google Scholar 

  2. Croarkin PE, Nakonezny PA, Wall CA, Murphy LL, Sampson SM, Frye MA, et al. Transcranial magnetic stimulation potentiates glutamatergic neurotransmission in depressed adolescents. Psychiatry Res Neuroimaging. 2016;247:25–33.

    Article  PubMed  Google Scholar 

  3. Bagga P, Pickup S, Crescenzi R, Martinez D, Borthakur A, D'Aquilla K, et al. In vivo GluCEST MRI: Reproducibility, background contribution and source of glutamate changes in the MPTP model of Parkinson’s disease. Sci Rep. 2018;8:2883.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Cai K, Haris M, Singh A, Kogan F, Greenberg JH, Hariharan H, et al. Magnetic resonance imaging of glutamate. Nat Med. 2012;18:302–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Cember A, Deck BL, Kelkar A, Faseyitan O, Zimmerman JP, Erickson B. et al. Glutamate-Weighted Magnetic Resonance Imaging (GluCEST) detects effects of transcranial magnetic stimulation to the motor cortex. NeuroImage. 2022;256:119191.

    Article  PubMed  Google Scholar 

Download references


The work was funded by RF1MH116920 and R01MH120811 to DJO.

Author information

Authors and Affiliations



JAD and DJO wrote the paper.

Corresponding author

Correspondence to Joseph A. Deluisi.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Deluisi, J.A., Oathes, D.J. Using metabolic imaging to investigate neuromodulatory mechanisms of rTMS. Neuropsychopharmacol. 48, 209–210 (2023).

Download citation

  • Published:

  • Issue Date:

  • DOI:


Quick links