This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 13 print issues and online access
$259.00 per year
only $19.92 per issue
Rent or buy this article
Get just this article for as long as you need it
Prices may be subject to local taxes which are calculated during checkout
Seabrook LT, Borgland SL. The orbitofrontal cortex, food intake and obesity. J Psychiatry Neurosci. 2020;45:190163.
Rudebeck PH, Rich EL. Orbitofrontal cortex. Curr Biol. 2018;28:R1083–R1088.
Thompson JL, Drysdale M, Baimel C, Kaur M, MacGowan T, Pitman KA, et al. Obesity-induced structural and neuronal plasticity in the lateral orbitofrontal cortex. Neuropsychopharmacology. 2017;42:1480–90.
Lau BK, Murphy-Royal C, Kaur M, Qiao M, Bains JS, Gordon GR, et al. Obesity-induced astrocyte dysfunction impairs heterosynaptic plasticity in the orbitofrontal cortex. Cell Rep. 2021;36:109563.
Lau BK, Cota D, Cristino L, Borgland SL. Endocannabinoid modulation of homeostatic and non-homeostatic feeding circuits. Neuropharmacology. 2017;124:38–51.
Gremel CM, Costa RM. Orbitofrontal and striatal circuits dynamically encode the shift between goal-directed and habitual actions. Nat Commun. 2013;4:2264.
SLB is supported by Koopmans Research Award, Canadian Institutes of Health Research operating grant (CIHR, FDN-147473) and a Canada Research Chair Tier 1 (950-232211).
The authors declare no competing interests.
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Seabrook, L.T., Borgland, S.L. Synaptic plasticity of the orbitofrontal cortex in obesity. Neuropsychopharmacol. 48, 257–258 (2023). https://doi.org/10.1038/s41386-022-01382-6