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Targeted and transient opening of the blood brain barrier in discrete neurocircuits and brain regions

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Fig. 1: Representative model for how focused ultrasound can be combined with nanoemulsions for precision drug delivery to the brain.


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We thank members of the Crowley and Medina labs for helpful discussions related to this topic.


NAC is supported by NIH grants R01AA029403-01A1, R21AA028088-01, and P50AA017823. SHM is supported by NIH grants R21DK128638-01A1, R35GM142902-01, and NSF grant DMR-1845053. NAC and SHM are jointly supported by the Benkovic Research Initiative

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NAC and SHM jointly conceived the topic for this commentary based on shared funding. NAC and SEM contributed equally to manuscript preparation.

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Correspondence to Nicole A. Crowley or Scott H. Medina.

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The authors declare no competing interests.

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Crowley, N.A., Medina, S.H. Targeted and transient opening of the blood brain barrier in discrete neurocircuits and brain regions. Neuropsychopharmacol. 48, 253–254 (2023).

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