Opioid dose regimen shapes mesolimbic adaptations

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    Yu G, Zhang F-Q, Tang S-E, Lai M-J, Su R-B, Gong Z-H. Continuous infusion versus intermittent bolus dosing of morphine: a comparison of analgesia, tolerance, and subsequent voluntary morphine intake. J Psychiatr Res. 2014;59:161–6.

    Article  Google Scholar 

  2. 2.

    Lee K, Vuong HE, Nusbaum DJ, Hsiao EY, Evans CJ, Taylor AMW. The gut microbiota mediates reward and sensory responses associated with regimen-selective morphine dependence. Neuropsychopharmacology. 2018;43:2606–14.

    CAS  Article  Google Scholar 

  3. 3.

    Lefevre EM, Pisansky MT, Toddes C, Baruffaldi F, Pravetoni M, Tian L, et al. Interruption of continuous opioid exposure exacerbates drug-evoked adaptations in the mesolimbic dopamine system. Neuropsychopharmacology (2020). https://doi.org/10.1038/s41386-020-0643-x

  4. 4.

    Scofield MD, Heinsbroek JA, Gipson CD, Kupchik YM, Spencer S, Smith ACW, et al. The nucleus accumbens: mechanisms of addiction across drug classes reflect the importance of glutamate homeostasis. Pharmacol Rev. 2016;68:816–71.

    CAS  Article  Google Scholar 

  5. 5.

    Dong B, Jaeger AM, Thiele DJ. Inhibiting heat shock factor 1 in cancer: a unique therapeutic opportunity. Trends Pharmacol Sci. 2019;40:986–1005.

    CAS  Article  Google Scholar 

  6. 6.

    Calderwood SK, Murshid A. Molecular chaperone accumulation in cancer and decrease in alzheimer’s disease: the potential roles of HSF1. Front Neurosci 2017;11:192.

    Article  Google Scholar 

  7. 7.

    Evans, CJ, Cahill, CM. Neurobiology of opioid dependence in creating addiction vulnerability. F1000Research 2016;5.

  8. 8.

    Savvas SM, Somogyi AA, White JM. The effect of methadone on emotional reactivity. Addiction. 2012;107:388–92.

    Article  Google Scholar 

  9. 9.

    Miles SW, Sheridan J, Russell B, Kydd R, Wheeler A, Walters C, et al. Extended-release methylphenidate for treatment of amphetamine/methamphetamine dependence: a randomized, double-blind, placebo-controlled trial. Addiction. 2013;108:1279–86.

    Article  Google Scholar 

  10. 10.

    Kerr CW, Drake J, Milch RA, Brazeau DA, Skretny JA, Brazeau GA, et al. Effects of methylphenidate on fatigue and depression: a randomized, double-blind, placebo-controlled trial. J Pain Symptom Manag. 2012;43:68–77.

    CAS  Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Catherine M. Cahill.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Cahill, C.M. Opioid dose regimen shapes mesolimbic adaptations. Neuropsychopharmacol. 45, 1777–1778 (2020). https://doi.org/10.1038/s41386-020-0679-y

Download citation

Search