Table 1 Study inclusion/exclusion criteria.

From: Increased subjective and reinforcing effects of initial nicotine exposure in young adults with attention deficit hyperactivity disorder (ADHD) compared to matched peers: results from an experimental model of first-time tobacco use

Inclusion criteriaExclusion criteria
◦ 18–25 years of age
◦ ADHD diagnosis:
 ◦ For ADHD Group: confirmed diagnosis, any subtype as determined by the clinician administered CAADID and clinical interview
 ◦ For Control Group:  NO diagnosis of ADHD as determined by clinician administered CAADID and clinical interview
◦ All participants will be non-smokers defined as never having smoked an entire cigarette and no tobacco use in the past 3 years
◦ Free from major medical problems and deemed healthy by the study physician
◦ No contraindications for treatment with nicotine nasal spray or placebo nasal spray
◦ DSM-IV Axis I or Axis II disorders that require additional pharmacological treatment or otherwise would interfere with participation in the present study
◦ Current use of any prescribed psychotropic medication in either group will be exclusionary, with the exception of ADHD participants currently being treated for ADHD that agree to discontinue their medication for the 5 half-life (~24–72 h) washout period prior to each experimental session
◦ For Control group, T-Score > 55 on Inattentive Symptoms, Hyperactive-Impulsive Symptoms, Total Symptoms or ADHD Index subscales of the CAARS
◦ Current substance abuse or dependence within the last 12 months
◦ Use of illegal drugs as measured by urine drug screen, expired breath alcohol level > 0.0
◦ Significant and chronic medical problems
◦ Pregnancy
◦ Estimated IQ < 80 on Kaufman Brief Intelligence Test, 2nd Edition (KBIT-II)
◦ Active use of any tobacco products
◦ Expired air CO level > 4 ppm; urine nicotine levels > 30 ng/ml
◦ Inability to understand written and/or spoken English language
◦ Reported uncertainty about being able to remain a nonsmoker in the coming year