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Novel models of drug relapse and craving after voluntary abstinence


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    Venniro M, Caprioli D, Shaham Y. Animal models of drug relapse and craving: from drug priming-induced reinstatement to incubation of craving after voluntary abstinence. Prog Brain Res. 2016;224:25–52.

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    Caprioli D, Venniro M, Zeric T, Li X, Adhikary S, Madangopal R, et al. Effect of the novel positive allosteric modulator of metabotropic glutamate receptor 2 AZD8529 on incubation of methamphetamine craving after prolonged voluntary abstinence in a rat model. Biol Psychiatry. 2015;78:463–73.

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    Venniro M, Zhang M, Shaham Y, Caprioli D. Incubation of methamphetamine but not heroin craving after voluntary abstinence in male and female rats. Neuropsychopharmacology. 2017;42:1126–35.

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    Caprioli D, Venniro M, Zhang M, Bossert JM, Warren BL, Hope BT, Shaham Y. Role of dorsomedial striatum neuronal ensembles in incubation of methamphetamine craving after voluntary abstinence. J Neurosci. 2017;37:1014–27.

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    Venniro M, Caprioli D, Zhang M, Whitaker LR, Zhang S, Warren BL, et al. The anterior insular cortex-->central amygdala glutamatergic pathway is critical to relapse after contingency management. Neuron. 2017;96:414–27 e418.

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    Venniro M, Zhang M, Caprioli D, Hoots JK, Golden SA, Heins C, et al. Volitional social interaction prevents drug addiction in rat models. Nature Neuroscience. 2018 (In press).

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The research was supported by the Intramural Research Program of NIDA (YS), NARSAD Distinguished Investigator Grant Award (YS), and a fellowship from the NIH Center on Compulsive Behaviors (MV).

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The authors declare no competing interests

Correspondence to Marco Venniro.

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