Fig. 4 | Neuropsychopharmacology

Fig. 4

From: Unique treatment potential of cannabidiol for the prevention of relapse to drug use: preclinical proof of principle

Fig. 4

Effects on experimental anxiety. Effects on experimental (EPM open arm time) in rats with a an alcohol (N = 12/group) or b cocaine (CBD: N = 9, VEH: N = 12) history. In both drug history groups CBD significantly reduced anxiety-like behavior, reflected by increased EPM open arm time as measured on PostTx day 2. c Dose dependence of the CBD effects on EPM open arm time measured in drug-naive rats on PostTx day 2 (N = 10/group). *p < 0.05 vs VEH.

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