Fig. 5 | Mucosal Immunology

Fig. 5

From: Alpha-galactosylceramide enhances mucosal immunity to oral whole-cell cholera vaccines

Fig. 5

α-GalCer enhances serum LPS and CTB-specific IgA titres compared to the oral vaccine with MS1342 V. cholerae/CTB alone. Mice were immunized orally with MS1342 V. cholerae and CTB either with or without α-GalCer or CT as an adjuvant. Serum was collected on day 41. Inaba LPS –specific (a, c) and CTB-specific (b, d) IgA as well as IgG1 antibody titres were determined by end-point ELISA. Graphs present mean titres (+SEM) for five mice per experimental group. No adjuvant versus α-GalCer or CT: **p < 0.01, ***p < 0.001

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