Fig. 3 | Mucosal Immunology

Fig. 3

From: Alpha-galactosylceramide enhances mucosal immunity to oral whole-cell cholera vaccines

Fig. 3

α-GalCer promotes Peyer’s patch Th1 but not Th17 responses after oral vaccination in female C57BL/6 mice. Mice were immunized orally with Dukoral® either with or without α-GalCer or CT as an adjuvant. Peyer’s patch (PP) cells were processed on day 42 and stimulated with 4 × 106 Dukoral® bacteria. Seventy-two hours post-stimulation, IFNy (a) and IL-17A (b) secretion was measured in supernatants by ELISA. Graphs present IFNy and IL-17A concentrations in supernatants (+SEM) for five mice per experimental group