Fig. 1 | Mucosal Immunology

Fig. 1

From: Alpha-galactosylceramide enhances mucosal immunity to oral whole-cell cholera vaccines

Fig. 1

α-GalCer enhances antigen-specific faecal IgA, serum IgA and IgG1 responses after oral vaccination compared to Dukoral® alone in female C57BL/6 mice. Mice were immunized orally with Dukoral® either with or without α-GalCer or CT as an adjuvant. Faecal pellets and sera were collected on day 41 and 42, respectively. Bacteria-specific and CTB–specific IgA responses in faecal pellets (a, b) and serum (c, d) as well as bacteria-specific and CTB-specific IgG1 responses in serum (e, f) were measured and antibody titres were determined by end-point ELISA. Graphs present mean titres (+SEM) for five mice per experimental group. *p < 0.05, **p < 0.01