Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

KKK879-881 motif is an ER-retention signal in GluN2A-NMDA receptor

Molecular Psychiatry volume 27, page 3115 (2022)Cite this article

Fig. 1 Mutations in KKK879-881 motif enhanced surface expression of GluN2A-NMDA receptor. HA-tagged GluN2A and mutations were co-expressed with GluN1 in HEK293T cells. GluN2A_3A, residues KKK879-881 mutated to alanine residues. For more information, please refer to the article by Li et al., in this issue.

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

Buy

All prices are NET prices.

Author information

Authors and Affiliations

  1. Ministry of Education Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Department of Neurology, Drum Tower Hospital, Medical School, Nanjing University, Nanjing, 210032, China

    Qing-Qing Li, Jiang Chen, Jia-Hui Sun, Yan-Yu Zang, Guiquan Chen, Yun Xu & Yun Stone Shi

  2. Department of Prenatal Diagnosis, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, 210004, China

    Ping Hu, Hao-Yang Feng, Feng-Chang Qiao & Zhengfeng Xu

  3. Department of Anesthesiology and Perioperative Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China

    Min Jia & Jian-Jun Yang

  4. State Key Laboratory of Pharmaceutical Biotechnology, National Resource Center for Mutant Mice, Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, 210032, China

    Jia-Hui Sun, Yan-Yu Zang, Guiquan Chen, Yun Xu & Yun Stone Shi

  5. Department of Orthopaedics, Luhe People’s Hospital Affiliated to Yangzhou University, Nanjing, 211500, China

    Yong-Yun Shi

  6. State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650201, China

    Nengyin Sheng

  7. Chemistry and Biomedicine Innovation Center, Nanjing University, Nanjing, 210032, China

    Yun Stone Shi

  8. Guangdong Institute of Intelligence Science and Technology, Zhuhai, 519031, China

    Yun Stone Shi

Authors
  1. Qing-Qing Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jiang Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ping Hu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Min Jia
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jia-Hui Sun
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Hao-Yang Feng
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Feng-Chang Qiao
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Yan-Yu Zang
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Yong-Yun Shi
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Guiquan Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Nengyin Sheng
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. Yun Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  13. Jian-Jun Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

  14. Zhengfeng Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  15. Yun Stone Shi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Jian-Jun Yang, Zhengfeng Xu or Yun Stone Shi.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Li, QQ., Chen, J., Hu, P. et al. KKK879-881 motif is an ER-retention signal in GluN2A-NMDA receptor. Mol Psychiatry 27, 3115 (2022). https://doi.org/10.1038/s41380-022-01868-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41380-022-01868-1

Search

Advanced search

Quick links