Table 2 Transcriptome analysis of differentially expressed genes in hiPSCs-derived cortical neurons

From: Correction: Neurobiological roots of psychopathy

Ensembl ID HGNC symbol Gene description Average expression Log2 fold change P-value Adjusted p-value
Violent vs. control
  ENSG00000233913 RPL10P9 Ribosomal protein L10 pseudogene 9 98,909 3433 8.26E−10 4.29E−05
  ENSG00000268912    79,387 2447 3.48E−09 9.06E−05
  ENSG00000131849 ZNF132 Zinc finger protein 132 138,380 2407 4.37E−08 7.57E−04
  ENSG00000256299    21,891 1526 3.39E−06 4.40E−02
Violent vs. control + nonviolent
  ENSG00000233913 RPL10P9 Ribosomal protein L10 pseudogene 9 98,909 3686 6.13E−10 1.84E−05
  ENSG00000182397 DNM1P46 Dynamin 1 pseudogene 46 16,689 −1595 1.70E−07 2.13E−03
  ENSG00000211459 MT-RNR1 Mitochondrially encoded 12 S RNA 3236,254 −2687 2.12E−07 2.13E−03
  ENSG00000138347 MYPN Myopalladin 7066 −2990 4.20E−07 3.16E−03
  ENSG00000023839 ABCC2 ATP binding cassette subfamily C member 2 19,849 −1972 1.76E−06 1.01E−02
  ENSG00000128284 APOL3 Apolipoprotein L3 13,244 −2741 2.02E−06 1.01E−02
  ENSG00000235683    4804 −2446 5.86E−06 1.82E−02
  ENSG00000140678 ITGAX Integrin subunit alpha X 13,142 −2747 6.24E−06 1.82E−02
  ENSG00000210151 MT-TS1 Mitochondrially encoded tRNA serine 1 (UCN) 17,046 −2165 7.14E−06 1.82E−02
  ENSG00000172738 TMEM217 Transmembrane protein 217 40,619 −1633 7.58E−06 1.82E−02
  ENSG00000179776 CDH5 Cadherin 5 7101 −2516 8.16E−06 1.82E−02
  ENSG00000260075 NSFP1   7076 2313 8.31E−06 1.82E−02
  ENSG00000172785 CBWD1 COBW domain containing 1 320,593 1208 8.47E−06 1.82E−02
  ENSG00000204930 FAM221B Family with sequence similarity 221 member B 7214 −2535 1.06E−05 2.09E−02
  ENSG00000200503 SNORD115-5 Small nucleolar RNA, C/D box 115-5 28,237 2062 1.11E−05 2.09E−02
  ENSG00000225630 MTND2P28 Mitochondrially encoded NADH:ubiq. 86,559 −2017 1.36E−05 2.24E−02
  ENSG00000236064    9175 −2653 1.46E−05 2.24E−02
  ENSG00000253426    5636 −2501 1.49E−05 2.24E−02
  ENSG00000164659 KIAA1324L KIAA1324 like 1178,161 1248 1.56E−05 2.24E−02
  ENSG00000267334    6711 2063 1.56E−05 2.24E−02
  ENSG00000188585 CLEC20A C-type lectin domain containing 20A 3726 −2730 1.70E−05 2.33E−02
  ENSG00000013588 GPRC5A G protein-coupled receptor class C group 5 member A 19,264 −2356 2.02E−05 2.56E−02
  ENSG00000257335 MGAM MaltasE−glucoamylase 42,608 −1951 2.05E−05 2.56E−02
  ENSG00000198899 MT-ATP6 Mitochondrially encoded ATP synthase 6 629,862 −1705 2.53E−05 3.04E−02
  ENSG00000131042 LILRB2 Leukocyte immunoglobulin like receptor B2 2933 −2720 2.95E−05 3.41E−02
  ENSG00000279301 OR2T11 Olfactory receptor family 2 subfamily T member 11 4182 −2634 3.13E−05 3.46E−02
  ENSG00000268416    5112 −2644 3.22E−05 3.46E−02
  ENSG00000268912    79,387 1852 3.47E−05 3.59E−02
  ENSG00000252906 SCARNA3 Small Cajal body-specific RNA 3 35,106 1208 3.58E−05 3.59E−02
  ENSG00000124731 TREM1 Triggering receptor expressed on myeloid cells 1 5602 −2372 4.35E−05 4.10E−02
  ENSG00000101440 ASIP Agouti signaling protein 3816 −2555 4.36E−05 4.10E−02
  ENSG00000187812    7086 −2614 4.61E−05 4.20E−02
  ENSG00000131849 ZNF132 Zinc finger protein 132 138,380 1920 5.01E−05 4.43E−02
  ENSG00000060709 RIMBP2 RIMS binding protein 2 152,792 1619 5.68E−05 4.88E−02
  1. Only genes with adjusted p-value < 0.05 and at least twofold up- or downregulation are presented
  2. “Violent” indicates violent offenders, and “nonviolent” indicates individuals with substance abuse but without criminal behavior