Table 3 Significant Spearman rank correlations between tumor PSA score and Ki67 labeling index with other previously measured variables of prognostic significance (see Table 2 for references) describing tumor and surrounding normal prostate tissue (TINT) [37]

From: Immunoreactivity for prostate specific antigen and Ki67 differentiates subgroups of prostate cancer related to outcome

  Correlation coefficient for tumor PSA score Correlation coefficient for tumor Ki67 labeling index
Clinical markers
 Gleason score −0.54c (n = 346) 0.50c (n = 389)
 Tumor stage −0.41c (n = 339) 0.42c (n = 382)
 M stage −0.31c (n = 272) 0.33c (n = 301)
 Cancer (%) −0.47c (n = 346) 0.45c (n = 389)
 Overall survival 0.21c (n = 346) −0.15b (n = 389)
Tumor markers
 Ki67 (%) −0.46c (n = 331)  
 pEGF-R score −0.21b (n = 252) 0.28c (n = 293)
 pAkt score −0.31c (n = 255) 0.36c (n = 278)
 ErbB2 score −0.29c (n = 307) 0.29c (n = 350)
 Vascular density (%) −0.24c (n = 330) 0.28c (n = 381)
 Hyaluronic acid score (stroma) −0.18b (n = 334) 0.27c (n = 384)
 Mast cell density (%) 0.21c (n = 322) −0.13a (n = 362)
 Androgen receptor (%) (stroma) 0.17b (n = 329) −0.17b (n = 373)
 PDGFR-beta (stroma) (37) −0.15a (n = 248) 0.21c (n = 283)
 Caveolin-1 score (stroma) 0.25c (n = 326) −0.25c (n = 370)
 CD163 (%) −0.24b (n = 177)  
 Erg (positive or not) −0.39c (n = 315) 0.32c (n = 350)
TINT markers
 Ki67   0.17b (n = 360)
 pEGF-R −0.19b (n = 244) 0.25c (n = 284)
 PDGFR-beta (stroma) (37) −0.13a (n = 302) 0.15b (n = 344)
 Hyaluronic acid score (stroma) −0.14a (n = 318) 0.14b (n = 363)
 Mast cell density (%) −0.22c (n = 299)  
 Caveolin-1 score (stroma)   −0.11a (n = 352)
 Erg (positive or not)   0.16b (n = 331)