Table 1 Multivariate Cox analysis of PSA and Ki67 immunoreactivity and Gleason score (GS) in relation to cancer-specific survival of patients diagnosed at TUR-P and managed by watchful waiting

From: Immunoreactivity for prostate specific antigen and Ki67 differentiates subgroups of prostate cancer related to outcome

  HR 95% CI P
   Lower Upper  
GS ≤ 6, n = 131 1    
GS = 7, n = 47 3.8 1.8 8.1 4.8E-04
GS ≥ 8, n = 59 6.7 3.2 14 4.9E-07
PSA IR = 12, n = 132 1    
PSA IR < 12, n = 105 2.1 1.1 3.7 0.017
Ki67 (%) 1.05 1.0 1.1 0.038
  1. PSA immunoreactivity (IR) was dichotomized by the median value 9 as high (IR = 12) or low (<9). Fraction of Ki67 positive tumor cells was analyzed as a continuous variable