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LYMPHOMA

Romidepsin antagonism with CHOEP

Leukemia (2023)Cite this article

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Fig. 1

Data availability

Raw data were generated at the University of Texas MD Anderson Cancer Center. Derived data supporting the findings of this study are available from the corresponding author JLR upon reasonable request.

References

  1. Chiappella A, Dodero A, Evangelista A, Re A, Orsucci L, Usai SV, et al. Romidepsin-CHOEP followed by high-dose chemotherapy and stem-cell transplantation in untreated Peripheral T-Cell Lymphoma: results of the PTCL13 phase Ib/II study. Leukemia. 2023;37:433–40. https://doi.org/10.1038/s41375-022-01780-1.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Bachy E, Camus V, Thieblemont C, Sibon, D, Casasnovas, R, Ysebaert, L, et al. Romidepsin plus CHOP versus CHOP in patients with previously untreated peripheral T-cell lymphoma: Results of the Ro-CHOP Phase III study (Conducted by LYSA). J Clin Oncol. 2021. https://doi.org/10.1200/JCO.21.01815.

  3. Valdez BC, Li Y, Murray D, Brammer J, Liu Y, Hosing C, et al. Differential effects of histone deacetylase inhibitors on cellular drug transporters and their implications for using epigenetic modifiers in combination chemotherapy. Oncotarget. 2016;7:63829–38.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Cole SP, Deeley RG. Transport of glutathione and glutathione conjugates by MRP1. Trends Pharm Sci. 2006;27:438–46.

    Article  CAS  PubMed  Google Scholar 

  5. Valdez BC, Hassan M, Andersson BS. Development of an assay for cellular efflux of pharmaceutically active agents and its relevance to understanding drug interactions. Exp Hematol. 2017;52:65–71.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of Stem Cell Transplantation & Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, TX, USA

    J. L. Ramdial, B. C. Valdez, B. S. Andersson & Y. Nieto

Authors
  1. J. L. Ramdial
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  2. B. C. Valdez
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  3. B. S. Andersson
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  4. Y. Nieto
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Contributions

JLR, BSA, and YN contributed to writing in each section of the article. BV and BSA have made a substantial contribution to the concept and design of the article and research models in the laboratory.

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Correspondence to J. L. Ramdial.

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Ramdial, J.L., Valdez, B.C., Andersson, B.S. et al. Romidepsin antagonism with CHOEP. Leukemia (2023). https://doi.org/10.1038/s41375-023-01873-5

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